Serious symptoms at the beginning and development of kidney failure

Serious symptoms at the beginning and development of kidney failure

Symptoms and signs of the disease

Symptoms may vary from person to person. A person in the early stage of kidney disease may not experience symptoms or notice symptoms when they occur. When the kidneys fail to properly filter, and waste accumulates in the blood and body, leading to blood being excreted (increased nitrogen levels in the blood). Very low levels of blood transduction may produce, if any, few symptoms. If the disease progresses, symptoms become noticeable (if the deficiency is sufficient to cause the symptoms). Renal failure with noticeable symptoms is called urea toxicosis.

Symptoms of kidney failure include:

High levels of urea in the blood, which can lead to:

Vomiting or diarrhea (or both) that may lead to dehydration.

Nausea.

Lose weight.

Night urination.

Urinating more frequently, or in greater amounts than usual, with urine pallor.

Urinating less frequently, or in smaller amounts than usual, with dark urine.

Blood in the urine.

Pressure or difficulty passing urine.

Unusual amounts of urination, usually in large quantities.

The accumulation of phosphates in the blood that the diseased kidneys cannot filter and excrete, may cause:

Itch.

Bone damage.

Broken bone not being forced.

Muscle spasms (due to low calcium levels linked to high blood phosphates).

The accumulation of potassium in the blood that the diseased kidneys cannot filter and excrete (called hyperkalemia), may cause:

Abnormal heart rhythm.

Muscle paralysis.

Failure of the kidneys to remove excess fluid, may cause:

Swelling in the legs, ankles, feet, face, or hands.

Shortness of breath due to extra fluid on the lungs (may also be caused by anemia).

Polycystic kidney disease, which causes large fluid-filled cysts on the kidneys and sometimes the liver, may cause:

Back or side pain.

A healthy kidney produces an erythropoietin hormone that stimulates the bone marrow to make red blood cells that carry oxygen. If the kidneys fail, they produce less erythropoietin, which results in reduced red blood cell production to replace old or naturally broken red blood cells. As a result, the blood will carry less hemoglobin, a condition known as anemia. This may lead to:

Feeling tired or weak.

Memory problems.

Difficulty concentrating.

Dizziness.

Reduction of Blood pressure.

Usually, proteins are too large to pass through the kidneys, however, they are able to pass through damaged glomeruli. This does not cause symptoms until kidney damage occurs extensively, after which the symptoms will include:

Foam in the urine or bubbles in the urine.

Swelling of the hands, feet, abdomen, or face.

Other symptoms include:

Anorexia, bad taste in the mouth.

Difficulty sleeping (insomnia).

The skin is dark.

Excess protein in the blood.

With high doses of penicillin, people who suffer from kidney failure may experience a seizure.

Chronic kidney disease

Chronic kidney disease has many causes. The most common causes are diabetes and long-term, uncontrolled high blood pressure. Polycystic kidney disease is another known cause of chronic kidney disease. Most people with polycystic kidney disease have a family history of the disease. Other genetic diseases affect kidney function.

Excessive use of common medications such as ibuprofen and acetaminophen (Paracetamol) cause chronic kidney disease.

Some infectious disease agents, such as the Hanta virus, can attack the kidneys, causing kidney failure.

Genetic predisposition

An APOL1 protein core gene has been suggested as a major genetic risk site for a group of people of African descent for non-diabetic kidney failure, which includes HIV-related nephropathy, primary mono-gene forms for glomerular sclerosis. Focal glomeruli, and hypertension associated with chronic kidney disease that is not associated with other pathogens. It has been found that two West African variants in the APOL1 lipoprotein gene are associated with kidney disease in African Americans and Hispanics.

Reasons related to the same college

Injury to the kidneys and their inability to purify and filter blood and get rid of toxic substances.

Kidney infections such as kidney abscess, kidney atrophy, and tuberculosis of the kidneys.

Kidney falling from normal.

Schistosomiasis

It often affects people, especially in the countryside, and leads to complications in the kidneys.

Cystic disease of the kidneys

It is the presence of multiple bags in the kidneys and this causes an increase in the size of the kidney.

Stages of kidney failure

The stages of chronic renal insufficiency are five and are calculated using the patient's glomerular filtration rate.

Stage 1: Kidney function reduced with few symptoms.

The second and third phases: The need for care increases to reduce and treat kidney dysfunction.

Phases IV and V: The patient usually needs treatment and in the fifth stage the disease is considered severe and requires dialysis or a kidney transplant if possible.

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